Elevated HOX gene expression in acute myeloid leukemia is associated with NPM1 mutations and poor survival

Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic progenitor cells and the most common malignant myeloid disorder in adults. Several gene mutations such as in NPM1 (nucleophosmin 1) are involved in the pathogenesis and progression of AML. The aim of this study was to identify genes...

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Dades bibliogràfiques
Publicat a:J Adv Res
Autors principals: Nagy, Ádám, Ősz, Ágnes, Budczies, Jan, Krizsán, Szilvia, Szombath, Gergely, Demeter, Judit, Bödör, Csaba, Győrffy, Balázs
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614546/
https://ncbi.nlm.nih.gov/pubmed/31333881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2019.05.006
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