Elevated HOX gene expression in acute myeloid leukemia is associated with NPM1 mutations and poor survival

Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic progenitor cells and the most common malignant myeloid disorder in adults. Several gene mutations such as in NPM1 (nucleophosmin 1) are involved in the pathogenesis and progression of AML. The aim of this study was to identify genes...

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Detalhes bibliográficos
Publicado no:J Adv Res
Main Authors: Nagy, Ádám, Ősz, Ágnes, Budczies, Jan, Krizsán, Szilvia, Szombath, Gergely, Demeter, Judit, Bödör, Csaba, Győrffy, Balázs
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614546/
https://ncbi.nlm.nih.gov/pubmed/31333881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2019.05.006
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