Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model

Human iPSC-derived engineered heart tissue (hEHT) has been used to remuscularize injured hearts in a guinea pig infarction model. While beneficial effects on cardiac remodeling have been demonstrated, the arrhythmogenic potential of hEHTs is a major concern. We investigated whether hiPSC-derived hEH...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pecha, Simon, Yorgan, Kaja, Röhl, Matti, Geertz, Birgit, Hansen, Arne, Weinberger, Florian, Sehner, Susanne, Ehmke, Heimo, Reichenspurner, Hermann, Eschenhagen, Thomas, Schwoerer, Alexander Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614415/
https://ncbi.nlm.nih.gov/pubmed/31285568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46409-z
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