The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation

The multi-subunit C-terminal to LisH (CTLH) complex is the mammalian homologue of the yeast Gid E3 ubiquitin ligase complex. In this study, we investigated the human CTLH complex and characterized its E3 ligase activity. We confirm that the complex immunoprecipitated from human cells comprises RanBP...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Maitland, Matthew E. R., Onea, Gabriel, Chiasson, Christopher A., Wang, Xu, Ma, Jun, Moor, Sarah E., Barber, Kathryn R., Lajoie, Gilles A., Shaw, Gary S., Schild-Poulter, Caroline
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614414/
https://ncbi.nlm.nih.gov/pubmed/31285494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46279-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky