FK506 prevented bone loss in streptozotocin-induced diabetic rats via enhancing osteogenesis and inhibiting adipogenesis

BACKGROUND: Type 1 diabetes mellitus (DM) is associated with severe osteoporosis, which is still a great challenge in the clinic. This work aimed to investigate the skeletal effects of FK506 in a rat model of streptozocin induced type 1 DM. METHODS: Rats were divided into three groups: control (CTL)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Transl Med
Prif Awduron: Ni, Li-Hua, Tang, Ri-Ning, Yuan, Cheng, Song, Kai-Yun, Wang, Li-Ting, Wang, Xiao-Chen, Zhang, Yu-Xia, Zhang, Xiao-Liang, Zhu, Dong-Dong, Liu, Bi-Cheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: AME Publishing Company 2019
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614318/
https://ncbi.nlm.nih.gov/pubmed/31355232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.05.44
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