Memantine Improves Cognitive Function and Alters Hippocampal and Cortical Proteome in Triple Transgenic Mouse Model of Alzheimer's Disease

Memantine is a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist clinically approved for moderate-to-severe Alzheimer's disease (AD) to improve cognitive functions. There is no report about the proteomic alterations induced by memantine in AD mouse model yet. In this study, we in...

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Dettagli Bibliografici
Pubblicato in:Exp Neurobiol
Autori principali: Zhou, Xinhua, Wang, Liang, Xiao, Wei, Su, Zhiyang, Zheng, Chengyou, Zhang, Zaijun, Wang, Yuqiang, Xu, Benhong, Yang, Xifei, Hoi, Maggie Pui Man
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society for Brain and Neural Science 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614075/
https://ncbi.nlm.nih.gov/pubmed/31308798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2019.28.3.390
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