Mitochondrial Molecular Abnormalities Revealed by Proteomic Analysis of Hippocampal Organelles of Mice Triple Transgenic for Alzheimer Disease

Mitochondrial dysfunction is implicated in the pathogenesis of Alzheimer’s disease (AD). However, the precise mitochondrial molecular deficits in AD remain poorly understood. Mitochondrial and nuclear proteomic analysis in mature male triple transgenic AD mice (PS1M146V/APPSwe/TauP301L) by two-dimen...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Yu, Haitao, Lin, Xuemei, Wang, Dian, Zhang, Zaijun, Guo, Yi, Ren, Xiaohu, Xu, Benhong, Yuan, Jianhui, Liu, Jianjun, Spencer, Peter S., Wang, Jian-Zhi, Yang, Xifei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854685/
https://ncbi.nlm.nih.gov/pubmed/29593495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00074
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