TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice

Transient receptor potential channel 1 (TRPC1) is widely expressed throughout the nervous system, while its biological role remains unclear. In this study, we showed that TRPC1 deletion caused striatal neuronal loss and significantly increased TUNEL-positive and 8-hydroxy-2′-deoxyguanosine (8-OHdG)...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Wang, Dian, Yu, Haitao, Xu, Benhong, Xu, Hua, Zhang, Zaijun, Ren, Xiaohu, Yuan, Jianhui, Liu, Jianjun, Guo, Yi, Spencer, Peter S., Yang, Xifei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870053/
https://ncbi.nlm.nih.gov/pubmed/29615894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00072
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