The First Generation of iPSC Line from a Korean Alzheimer's Disease Patient Carrying APP-V715M Mutation Exhibits a Distinct Mitochondrial Dysfunction

Alzheimer's Disease (AD) is a progressive neurodegenerative disease, which is pathologically defined by the accumulation of amyloid plaques and hyper-phosphorylated tau aggregates in the brain. Mitochondrial dysfunction is also a prominent feature in AD, and the extracellular Aβ and phosphoryla...

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Detalhes bibliográficos
Publicado no:Exp Neurobiol
Main Authors: Li, Ling, Roh, Jee Hoon, Kim, Hee Jin, Park, Hyun Jung, Kim, Minchul, Koh, Wonyoung, Heo, Hyohoon, Chang, Jong Wook, Nakanishi, Mahito, Yoon, Taeyoung, Na, Duk L., Song, Jihwan
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Brain and Neural Science 2019
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614069/
https://ncbi.nlm.nih.gov/pubmed/31308793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2019.28.3.329
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