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Cross talk between SOD1 and the mitochondrial UPR in cancer and neurodegeneration

The mitochondrial unfolded protein response (UPR(mt)) is rapidly gaining attention. While the CHOP (ATF4/5) axis of the UPR(mt) was the first to be described, other axes have subsequently been reported. Validation of this complex pathway in C. elegans has been extensively studied. However, validatio...

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Publicado en:Mol Cell Neurosci
Main Authors: Gomez, Maria, Germain, Doris
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614005/
https://ncbi.nlm.nih.gov/pubmed/31028834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2019.04.003
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