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SOD2 to SOD1 Switch in Breast Cancer

Cancer cells are characterized by elevated levels of reactive oxygen species, which are produced mainly by the mitochondria. The dismutase SOD2 localizes in the matrix and is a major antioxidant. The activity of SOD2 is regulated by the deacetylase SIRT3. Recent studies indicated that SIRT3 is decre...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Papa, Luena, Hahn, Mary, Marsh, Ellen L., Evans, Bradley S., Germain, Doris
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937618/
https://ncbi.nlm.nih.gov/pubmed/24448804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.526475
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