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Estrogen receptor mediates a distinct mitochondrial unfolded protein response

Unfolded protein responses (UPRs) of the endoplasmic reticulum and mitochondrial matrix have been described. Here, we show that the accumulation of proteins in the inter-membrane space (IMS) of mitochondria in the breast cancer cell line MCF-7 activates a distinct UPR. Upon IMS stress, overproductio...

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Detalhes bibliográficos
Main Authors: Papa, Luena, Germain, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078808/
https://ncbi.nlm.nih.gov/pubmed/21486948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.078220
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