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Estrogen receptor mediates a distinct mitochondrial unfolded protein response
Unfolded protein responses (UPRs) of the endoplasmic reticulum and mitochondrial matrix have been described. Here, we show that the accumulation of proteins in the inter-membrane space (IMS) of mitochondria in the breast cancer cell line MCF-7 activates a distinct UPR. Upon IMS stress, overproductio...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Company of Biologists
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078808/ https://ncbi.nlm.nih.gov/pubmed/21486948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.078220 |
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