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Reduction in Urinary Oxalate Excretion in Mouse Models of Primary Hyperoxaluria by RNA interference Inhibition of Liver Lactate Dehydrogenase Activity.
The Primary Hyperoxaluria’s (PH) are rare autosomal recessive disorders characterized by elevated oxalate production. PH patients suffer recurrent calcium oxalate kidney stone disease, and in severe cases end stage renal disease. Recent evidence has shown that RNA interference may be a suitable appr...
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| Publicado en: | Biochim Biophys Acta Mol Basis Dis |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613992/ https://ncbi.nlm.nih.gov/pubmed/31055082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.04.017 |
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