Dodecyl creatine ester-loaded nanoemulsion as a promising therapy for creatine transporter deficiency

Creatine transporter (CrT) deficiency is an X-linked intellectual disability caused by mutations of CrT. AIM: This work focus on the preclinical development of a new therapeutic approach based on a microemulsion (ME) as drug delivery system for dodecyl creatine ester (DCE). MATERIALS & METHODS:...

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Veröffentlicht in:Nanomedicine (Lond)
Hauptverfasser: Ullio-Gamboa, Gabriela, Udobi, Kenea C, Dezard, Sophie, Perna, Marla K, Miles, Keila N, Costa, Narciso, Taran, Frédéric, Pruvost, Alain, Benoit, Jean-Pierre, Skelton, Matthew R, de Lonlay, Pascale, Mabondzo, Aloïse
Format: Artigo
Sprache:Inglês
Veröffentlicht: Future Medicine Ltd 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613044/
https://ncbi.nlm.nih.gov/pubmed/31038003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2019-0059
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