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Effects of purine-scaffold inhibitors on HUVECs: Involvement of the purinergic pathway and interference with ATP. Implications for preventing the adverse effects of extracellular Grp94

BACKGROUND: Extracellular Glucose-regulated protein94 (Grp94) is linked to pathological conditions disrupting the obligatory intracellular location of this Heat Shock Protein (HSP). In plasma, Grp94 is linked to IgG in complexes that drive adverse effects on vascular cells and are biomarker of gastr...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Tramentozzi, Elisa, Finotti, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611975/
https://ncbi.nlm.nih.gov/pubmed/31317075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100661
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