Retinal myeloid cells regulate tip cell selection and vascular branching morphogenesis via Notch ligand Delta-like 1

During angiogenesis, single endothelial cells (EC) specialize into tip cells that guide vessel sprouting towards growth factor gradients and instruct the adjacent vessel stalk. The balance between tip and stalk cells is regulated by endothelial Notch signalling through the expression of Notch ligand...

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Pubblicato in:Sci Rep
Autori principali: Haupt, Fabian, Krishnasamy, Kashyap, Napp, L. Christian, Augustynik, Michael, Limbourg, Anne, Gamrekelashvili, Jaba, Bauersachs, Johann, Haller, Hermann, Limbourg, Florian P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611798/
https://ncbi.nlm.nih.gov/pubmed/31278348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46308-3
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