Regulation of monocyte cell fate by blood vessels mediated by Notch signalling

A population of monocytes, known as Ly6C(lo) monocytes, patrol blood vessels by crawling along the vascular endothelium. Here we show that endothelial cells control their origin through Notch signalling. Using combinations of conditional genetic deletion strategies and cell-fate tracking experiments...

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Publicado no:Nat Commun
Main Authors: Gamrekelashvili, Jaba, Giagnorio, Roberto, Jussofie, Jasmin, Soehnlein, Oliver, Duchene, Johan, Briseño, Carlos G., Ramasamy, Saravana K., Krishnasamy, Kashyap, Limbourg, Anne, Häger, Christine, Kapanadze, Tamar, Ishifune, Chieko, Hinkel, Rabea, Radtke, Freddy, Strobl, Lothar J., Zimber-Strobl, Ursula, Napp, L. Christian, Bauersachs, Johann, Haller, Hermann, Yasutomo, Koji, Kupatt, Christian, Murphy, Kenneth M., Adams, Ralf H., Weber, Christian, Limbourg, Florian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013671/
https://ncbi.nlm.nih.gov/pubmed/27576369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12597
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