Alopecia areata patients show deficiency of FOXP(3)+CD(39)+ T regulatory cells and clonotypic restriction of Treg TCRβ-chain, which highlights the immunopathological aspect of the disease

Alopecia areata (AA) is a hair loss disorder resulting from an autoimmune reaction against hair follicles. T-helper 1 cells are a major contributor to this disorder, but little is known about the role of T-regulatory cells (Tregs) in AA. Here, we analysed the distribution of circulating Treg subsets...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Hamed, Fatma N., Åstrand, Annika, Bertolini, Marta, Rossi, Alfredo, Maleki-Dizaji, Afsaneh, Messenger, Andrew G., McDonagh, Andrew J. G., Tazi-Ahnini, Rachid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611701/
https://ncbi.nlm.nih.gov/pubmed/31277078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210308
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