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Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in Plasmodium falciparum

In their competition for hosts, parasites with antigens that are novel to the host immune system will be at a competitive advantage. The resulting frequency-dependent selection can structure parasite populations into strains of limited genetic overlap. For the causative agent of malaria, Plasmodium...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Pilosof, Shai, He, Qixin, Tiedje, Kathryn E., Ruybal-Pesántez, Shazia, Day, Karen P., Pascual, Mercedes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611651/
https://ncbi.nlm.nih.gov/pubmed/31233490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000336
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