Congenital lipodystrophy induces severe osteosclerosis

Berardinelli-Seip congenital generalized lipodystrophy is associated with increased bone mass suggesting that fat tissue regulates the skeleton. Because there is little mechanistic information regarding this issue, we generated "fat-free" (FF) mice completely lacking visible visceral, subc...

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Publicado en:PLoS Genet
Autores principales: Zou, Wei, Rohatgi, Nidhi, Brestoff, Jonathan R., Zhang, Yan, Scheller, Erica L., Craft, Clarissa S., Brodt, Michael D., Migotsky, Nicole, Silva, Matthew J., Harris, Charles A., Teitelbaum, Steven L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611650/
https://ncbi.nlm.nih.gov/pubmed/31233501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008244
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