Site-Specific Reprogramming of Macrophage Responsiveness to Bacterial Lipopolysaccharide in Obesity

The mechanisms by which obesity may alter immune responses to pathogens are poorly understood. The present study assessed whether the intrinsic responsiveness of resident macrophages to bacterial lipopolysaccharide (LPS) is reprogrammed in high-fat diet (HFD)-induced obesity. Macrophages from adipos...

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Pubblicato in:Front Immunol
Autori principali: Komegae, Evilin N., Fonseca, Monique T., da Silveira Cruz-Machado, Sanseray, Turato, Walter M., Filgueiras, Luciano R., Markus, Regina P., Steiner, Alexandre A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611339/
https://ncbi.nlm.nih.gov/pubmed/31316525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01496
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