Site-Specific Reprogramming of Macrophage Responsiveness to Bacterial Lipopolysaccharide in Obesity

The mechanisms by which obesity may alter immune responses to pathogens are poorly understood. The present study assessed whether the intrinsic responsiveness of resident macrophages to bacterial lipopolysaccharide (LPS) is reprogrammed in high-fat diet (HFD)-induced obesity. Macrophages from adipos...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Komegae, Evilin N., Fonseca, Monique T., da Silveira Cruz-Machado, Sanseray, Turato, Walter M., Filgueiras, Luciano R., Markus, Regina P., Steiner, Alexandre A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611339/
https://ncbi.nlm.nih.gov/pubmed/31316525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01496
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