Site-Specific Reprogramming of Macrophage Responsiveness to Bacterial Lipopolysaccharide in Obesity

The mechanisms by which obesity may alter immune responses to pathogens are poorly understood. The present study assessed whether the intrinsic responsiveness of resident macrophages to bacterial lipopolysaccharide (LPS) is reprogrammed in high-fat diet (HFD)-induced obesity. Macrophages from adipos...

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Vydáno v:Front Immunol
Hlavní autoři: Komegae, Evilin N., Fonseca, Monique T., da Silveira Cruz-Machado, Sanseray, Turato, Walter M., Filgueiras, Luciano R., Markus, Regina P., Steiner, Alexandre A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611339/
https://ncbi.nlm.nih.gov/pubmed/31316525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01496
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