Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial

BACKGROUND: Lacunar stroke, a frequent clinical manifestation of small vessel disease (SVD), differs pathologically from other ischaemic stroke subtypes and has no specific long-term secondary prevention. Licenced drugs, isosorbide mononitrate (ISMN) and cilostazol, have relevant actions to prevent...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:EClinicalMedicine
Auteurs principaux: Blair, Gordon W., Appleton, Jason P., Flaherty, Katie, Doubal, Fergus, Sprigg, Nikola, Dooley, Richard, Richardson, Carla, Hamilton, Iona, Law, Zhe Kang, Shi, Yulu, Stringer, Michael S., Thrippleton, Michael J., Boyd, Julia, Shuler, Kirsten, Bath, Philip M., Wardlaw, Joanna M.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611094/
https://ncbi.nlm.nih.gov/pubmed/31317131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2019.04.001
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires