Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial

BACKGROUND: Lacunar stroke, a frequent clinical manifestation of small vessel disease (SVD), differs pathologically from other ischaemic stroke subtypes and has no specific long-term secondary prevention. Licenced drugs, isosorbide mononitrate (ISMN) and cilostazol, have relevant actions to prevent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EClinicalMedicine
Egile Nagusiak: Blair, Gordon W., Appleton, Jason P., Flaherty, Katie, Doubal, Fergus, Sprigg, Nikola, Dooley, Richard, Richardson, Carla, Hamilton, Iona, Law, Zhe Kang, Shi, Yulu, Stringer, Michael S., Thrippleton, Michael J., Boyd, Julia, Shuler, Kirsten, Bath, Philip M., Wardlaw, Joanna M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611094/
https://ncbi.nlm.nih.gov/pubmed/31317131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2019.04.001
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