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A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos
BACKGROUND: The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been partially studied, and evidence shows that MEK signalling plays a limited role in t...
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| Publicado no: | BMC Dev Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610975/ https://ncbi.nlm.nih.gov/pubmed/31272387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-019-0193-9 |
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