Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure

BACKGROUND: The chemokine receptor CCR7, expressed on various immune cells, is associated with cell migration and lympho-node homing. Mice lacking Ccr7 are protected from diet-induced obesity and subsequent insulin resistance. We evaluated the mechanism underlying these protective effects from the s...

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Bibliografiske detaljer
Udgivet i:Nutr Metab (Lond)
Main Authors: Sano, Tomomi, Sanada, Taiki, Sotomaru, Yusuke, Shinjo, Takanori, Iwashita, Misaki, Yamashita, Akiko, Fukuda, Takao, Sanui, Terukazu, Asano, Tomoichiro, Kanematsu, Takashi, Nishimura, Fusanori
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610939/
https://ncbi.nlm.nih.gov/pubmed/31312229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-019-0372-5
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