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The pluripotency regulator PRDM14 requires hematopoietic regulator CBFA2T3 to initiate leukemia in mice
Prdm14 is a pluripotency regulator central to embryonic stem cell identity and primordial germ cell specification. Genomic regions containing PRDM14 are often amplified leading to mis-expression in human cancer. Prdm14 expression in mouse hematopoietic stem cells (HSCs) leads to progenitor cell expa...
Shranjeno v:
| izdano v: | Mol Cancer Res |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610658/ https://ncbi.nlm.nih.gov/pubmed/31015254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1327 |
| Oznake: |
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