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Using genetically incorporated unnatural amino acids to control protein functions in mammalian cells

Genetic code expansion allows unnatural (non-canonical) amino acid incorporation into proteins of interest by repurposing the cellular translation machinery. The development of this technique has enabled site-specific incorporation of many structurally and chemically diverse amino acids, facilitatin...

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Bibliographic Details
Published in:Essays Biochem
Main Authors: Nödling, Alexander R., Spear, Luke A., Williams, Thomas L., Luk, Louis Y.P., Tsai, Yu-Hsuan
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610526/
https://ncbi.nlm.nih.gov/pubmed/31092687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20180042
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