AAV9-Mediated Overexpression of TRPM4 Increases the Incidence of Stress-Induced Ventricular Arrhythmias in Mice

Ca(2+) activated non-selective (CAN) cation channels have been described in cardiomyocytes since the advent of the patch clamp technique. It has been hypothesized that this type of ion channel contributes to the triggering of cardiac arrhythmias. TRPM4 is to date the only molecular candidate for a C...

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Vydáno v:Front Physiol
Hlavní autoři: Pironet, Andy, Syam, Ninda, Vandewiele, Frone, Van den Haute, Chris, Kerselaers, Sara, Pinto, Silvia, Vande Velde, Greetje, Gijsbers, Rik, Vennekens, Rudi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610516/
https://ncbi.nlm.nih.gov/pubmed/31316392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00802
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