Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity

CANTOS (Canakinumab Antiinflammatory Thrombosis Outcome Study) confirmed interleukin (IL)–1β as an appealing therapeutic target for human atherosclerosis and related complications. However, there are serious gaps in our understanding of IL-1 production in atherosclerosis. Herein the authors show tha...

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Detalles Bibliográficos
Publicado en:JACC Basic Transl Sci
Main Authors: Jiang, Xintong, Wang, Feilong, Wang, Yajuan, Gisterå, Anton, Roy, Joy, Paulsson-Berne, Gabrielle, Hedin, Ulf, Lerman, Amir, Hansson, Göran K., Herrmann, Joerg, Yan, Zhong-qun
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
Assuntos:
CLINICAL RESEARCH
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610158/
https://ncbi.nlm.nih.gov/pubmed/31312755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.02.007
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