FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

The glutamate transporter 1 (GLT1) is upregulated during astrocyte development and maturation in vivo and is vital for astrocyte function. Yet it is expressed at low levels by most cultured astrocytes. We previously showed that maturation of human and mouse stem cell-derived astrocytes – including f...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Savchenko, Ekaterina, Teku, Gabriel N., Boza-Serrano, Antonio, Russ, Kaspar, Berns, Manon, Deierborg, Tomas, Lamas, Nuno J., Wichterle, Hynek, Rothstein, Jeffrey, Henderson, Christopher E., Vihinen, Mauno, Roybon, Laurent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610107/
https://ncbi.nlm.nih.gov/pubmed/31270389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46110-1
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