Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes

Differentiation of astrocytes from human stem cells has significant potential for analyzing their role in normal brain function and disease, but existing protocols generate only immature astrocytes. Using early neuralization, we generated spinal cord astrocytes from mouse or human embryonic (ESCs) o...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Roybon, Laurent, Lamas, Nuno J., Garcia, Alejandro D., Yang, Eun Ju, Sattler, Rita, Lewis, Vernice J., Kim, Yoon A., Kachel, C. Alan, Rothstein, Jeffrey D., Przedborski, Serge, Wichterle, Hynek, Henderson, Christopher E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229657/
https://ncbi.nlm.nih.gov/pubmed/23994478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.021
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