Neuropathic Pain Induced Alterations in the Opioidergic Modulation of a Descending Pain Facilitatory Area of the Brain

Opioids play a major role at descending pain modulation but the effects of neuropathic pain on the brain opioidergic system remain understudied. Since descending facilitation is enhanced during neuropathic pain, we studied the opioidergic modulation of the dorsal reticular nucleus (DRt), a medullary...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Costa, Ana Rita, Carvalho, Paulina, Flik, Gunnar, Wilson, Steven P., Reguenga, Carlos, Martins, Isabel, Tavares, Isaura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610065/
https://ncbi.nlm.nih.gov/pubmed/31316354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00287
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