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Molecular Depletion of Descending Serotonin Unmasks Its Novel Facilitatory Role in the Development of Persistent Pain

Recent studies indicate that persistent pain after tissue or nerve injury is accompanied by an enhanced net descending facilitatory drive that contributes to an amplification and spread of pain. Although 5-HT-containing neurons in the rostral ventromedial medulla (RVM) provide the major descending s...

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Detalhes bibliográficos
Main Authors: Wei, Feng, Dubner, Ronald, Zou, Shiping, Ren, Ke, Bai, Guang, Wei, Dong, Guo, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902253/
https://ncbi.nlm.nih.gov/pubmed/20573908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5389-09.2010
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