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Molecular Depletion of Descending Serotonin Unmasks Its Novel Facilitatory Role in the Development of Persistent Pain

Recent studies indicate that persistent pain after tissue or nerve injury is accompanied by an enhanced net descending facilitatory drive that contributes to an amplification and spread of pain. Although 5-HT-containing neurons in the rostral ventromedial medulla (RVM) provide the major descending s...

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Autors principals: Wei, Feng, Dubner, Ronald, Zou, Shiping, Ren, Ke, Bai, Guang, Wei, Dong, Guo, Wei
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902253/
https://ncbi.nlm.nih.gov/pubmed/20573908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5389-09.2010
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