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Transition to Persistent Orofacial Pain after Nerve Injury Involves Supraspinal Serotonin Mechanisms

The orofacial region is a major focus of chronic neuropathic pain conditions characterized by primary hyperalgesia at the site of injury and secondary hyperalgesia outside the injured zone. We have used a rat model of injury to the maxillary branch (V2) of the trigeminal nerve to produce constant an...

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Main Authors: Okubo, Masamichi, Castro, Alberto, Guo, Wei, Zou, Shiping, Ren, Ke, Wei, Feng, Keller, Asaf, Dubner, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640487/
https://ncbi.nlm.nih.gov/pubmed/23516281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3390-12.2013
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