Malonyl CoA Decarboxylase Inhibition Improves Cardiac Function Post-Myocardial Infarction

Alterations in cardiac energy metabolism after a myocardial infarction contribute to the severity of heart failure (HF). Although fatty acid oxidation can be impaired in HF, it is unclear if stimulating fatty acid oxidation is a desirable approach to treat HF. Both immediate and chronic malonyl coen...

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Veröffentlicht in:JACC Basic Transl Sci
Hauptverfasser: Wang, Wei, Zhang, Liyan, Battiprolu, Pavan K., Fukushima, Arata, Nguyen, Khanh, Milner, Kenneth, Gupta, Abhishek, Altamimi, Tariq, Byrne, Nikole, Mori, Jun, Alrob, Osama Abo, Wagg, Cory, Fillmore, Natasha, Wang, Shao-hua, Liu, Dongming M., Fu, Angela, Lu, Jenny Yinglin, Chaves, Mary, Motani, Alykhan, Ussher, John R., Reagan, Jeff D., Dyck, Jason R.B., Lopaschuk, Gary D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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PRECLINICAL RESEARCH
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609914/
https://ncbi.nlm.nih.gov/pubmed/31312761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.02.003
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