CADM1 associates with Hippo pathway core kinases; membranous co–expression of CADM1 and LATS2 in lung tumors predicts good prognosis

Cell adhesion molecule‐1 (CADM1) is a member of the immunoglobulin superfamily that functions as a tumor suppressor of lung tumors. We herein demonstrated that CADM1 interacts with Hippo pathway core kinases and enhances the phosphorylation of YAP1, and also that the membranous co–expression of CADM...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Ito, Takeshi, Nakamura, Atsuko, Tanaka, Ichidai, Tsuboi, Yumi, Morikawa, Teppei, Nakajima, Jun, Takai, Daiya, Fukayama, Masashi, Sekido, Yoshitaka, Niki, Toshiro, Matsubara, Daisuke, Murakami, Yoshinori
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609799/
https://ncbi.nlm.nih.gov/pubmed/31069869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14040
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