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Activation of The Phosphatidylcholine to Lysophosphatidylcholine Pathway Is Associated with Osteoarthritis Knee Cartilage Volume Loss Over Time

To identify serum biomarker(s) for predicting knee cartilage volume loss over time, we studied 139 knee osteoarthritis (OA) patients from a previous 24-month clinical trial cohort. Targeted metabolomic profiling was performed on serum collected at baseline. The pairwise metabolite ratios as proxies...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Zhai, Guangju, Pelletier, Jean-Pierre, Liu, Ming, Aitken, Dawn, Randell, Edward, Rahman, Proton, Jones, Graeme, Martel-Pelletier, Johanne
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609700/
https://ncbi.nlm.nih.gov/pubmed/31273319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46185-w
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