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Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis

Background: Glucocorticoid resistance—reduced function of the glucocorticoid receptor (GR)—is seen in many depressed patients. It is argued that this resistance to glucocorticoids leads to failure of normal feedback regulation on the immune system. High levels of pro-inflammatory cytokines result. P...

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Publicat a:Front Psychiatry
Autors principals: Perrin, Andrew J., Horowitz, Mark A., Roelofs, Jacob, Zunszain, Patricia A., Pariante, Carmine M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609575/
https://ncbi.nlm.nih.gov/pubmed/31316402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2019.00423
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