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Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis

Background: Glucocorticoid resistance—reduced function of the glucocorticoid receptor (GR)—is seen in many depressed patients. It is argued that this resistance to glucocorticoids leads to failure of normal feedback regulation on the immune system. High levels of pro-inflammatory cytokines result. P...

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Detalhes bibliográficos
Publicado no:Front Psychiatry
Main Authors: Perrin, Andrew J., Horowitz, Mark A., Roelofs, Jacob, Zunszain, Patricia A., Pariante, Carmine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609575/
https://ncbi.nlm.nih.gov/pubmed/31316402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2019.00423
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