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Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

The most striking morphologic change in neurons during normal aging is the accumulation of autophagic vacuoles filled with lipofuscin or neuromelanin pigments. These organelles are similar to those containing the ceroid pigments associated with neurologic disorders, particularly in diseases caused b...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Sulzer, David, Mosharov, Eugene, Talloczy, Zsolt, Zucca, Fabio A., Simon, John D., Zecca, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609458/
https://ncbi.nlm.nih.gov/pubmed/18384642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05385.x
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