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Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

The most striking morphologic change in neurons during normal aging is the accumulation of autophagic vacuoles filled with lipofuscin or neuromelanin pigments. These organelles are similar to those containing the ceroid pigments associated with neurologic disorders, particularly in diseases caused b...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Sulzer, David, Mosharov, Eugene, Talloczy, Zsolt, Zucca, Fabio A., Simon, John D., Zecca, Luigi
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609458/
https://ncbi.nlm.nih.gov/pubmed/18384642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05385.x
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