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Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

The hantavirus envelope glycoproteins Gn and Gc mediate virion assembly and cell entry, with Gc driving fusion of viral and endosomal membranes. Although the X-ray structures and overall arrangement of Gn and Gc on the hantavirus spikes are known, their detailed interactions are not. Here we show th...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bignon, Eduardo A, Albornoz, Amelina, Guardado-Calvo, Pablo, Rey, Félix A, Tischler, Nicole D
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609335/
https://ncbi.nlm.nih.gov/pubmed/31180319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46028
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