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Hantavirus Gn and Gc Glycoproteins Self-Assemble into Virus-Like Particles

How hantaviruses assemble and exit infected cells remains largely unknown. Here, we show that the expression of Andes (ANDV) and Puumala (PUUV) hantavirus Gn and Gc envelope glycoproteins lead to their self-assembly into virus-like particles (VLPs) which were released to cell supernatants. The viral...

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Detalhes bibliográficos
Main Authors: Acuña, Rodrigo, Cifuentes-Muñoz, Nicolás, Márquez, Chantal L., Bulling, Manuela, Klingström, Jonas, Mancini, Roberta, Lozach, Pierre-Yves, Tischler, Nicole D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911568/
https://ncbi.nlm.nih.gov/pubmed/24335294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03118-13
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