Loading...
The conformation and dynamics of P-glycoprotein in a lipid bilayer investigated by atomic force microscopy
The membrane-bound P-glycoprotein (Pgp) transporter plays a major role in human disease and drug disposition because of its ability to efflux a chemically diverse range of drugs through ATP hydrolysis and ligand-induced conformational changes. Deciphering these structural changes is key to understan...
Na minha lista:
| Udgivet i: | Biochem Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609289/ https://ncbi.nlm.nih.gov/pubmed/30121251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.08.017 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|