Loading...
Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation
The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-induced changes in liver oxygen homeostasis, we found that liver HIF-1α expression was increased mainly by soluble factors released from obese adipocyt...
Na minha lista:
| Udgivet i: | Sci Adv |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Association for the Advancement of Science
2019
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609217/ https://ncbi.nlm.nih.gov/pubmed/31281892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw4176 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|