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Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model

Trypanosoma cruzi infection results in debilitating cardiomyopathy, which is a major cause of mortality and morbidity in the endemic regions of Chagas disease (CD). The pathogenesis of Chagasic cardiomyopathy (CCM) has been intensely studied as a chronic inflammatory disease until recent observation...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Ayyappan, Janeesh Plakkal, lizardo, Kezia, Wang, Sean, Yurkow, Edward, Nagajyothi, Jyothi F
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609105/
https://ncbi.nlm.nih.gov/pubmed/30879276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2018.193
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