The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury

The repair of white matter damage is of paramount importance for functional recovery after brain injuries. Here, we report that interleukin-4 (IL-4) promotes oligodendrocyte regeneration and remyelination. IL-4 receptor expression was detected in a variety of glial cells after ischemic brain injury,...

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Publicat a:PLoS Biol
Autors principals: Zhang, Qingxiu, Zhu, Wen, Xu, Fei, Dai, Xuejiao, Shi, Ligen, Cai, Wei, Mu, Hongfeng, Hitchens, T. Kevin, Foley, Lesley M., Liu, Xiangrong, Yu, Fang, Chen, Jie, Shi, Yejie, Leak, Rehana K., Gao, Yanqin, Chen, Jun, Hu, Xiaoming
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608986/
https://ncbi.nlm.nih.gov/pubmed/31226122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000330
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