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Therapeutic Genome Mutagenesis Using Synthetic Donor DNA and Triplex-Forming Molecules

Genome mutagenesis can be achieved in a variety of ways, though a select few are suitable for therapeutic settings. Among them, the harnessing of intracellular homologous recombination affords the safety and efficacy profile suitable for such settings. Recombinagenic donor DNA and mutagenic triplex-...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Reza, Faisal, Glazer, Peter M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608751/
https://ncbi.nlm.nih.gov/pubmed/25408401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1862-1_4
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