Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography

Copper-containing nitrite reductases (CuNiRs) that convert NO(2) (−) to NO via a Cu(CAT)–His–Cys–Cu(ET) proton-coupled redox system are of central importance in nitrogen-based energy metabolism. These metalloenzymes, like all redox enzymes, are very susceptible to radiation damage from the intense s...

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Pubblicato in:IUCrJ
Autori principali: Halsted, Thomas P., Yamashita, Keitaro, Gopalasingam, Chai C., Shenoy, Rajesh T., Hirata, Kunio, Ago, Hideo, Ueno, Go, Blakeley, Matthew P., Eady, Robert R., Antonyuk, Svetlana V., Yamamoto, Masaki, Hasnain, S. Samar
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2019
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608623/
https://ncbi.nlm.nih.gov/pubmed/31316819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252519008285
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