Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography

Copper-containing nitrite reductases (CuNiRs) that convert NO(2) (−) to NO via a Cu(CAT)–His–Cys–Cu(ET) proton-coupled redox system are of central importance in nitrogen-based energy metabolism. These metalloenzymes, like all redox enzymes, are very susceptible to radiation damage from the intense s...

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Udgivet i:IUCrJ
Main Authors: Halsted, Thomas P., Yamashita, Keitaro, Gopalasingam, Chai C., Shenoy, Rajesh T., Hirata, Kunio, Ago, Hideo, Ueno, Go, Blakeley, Matthew P., Eady, Robert R., Antonyuk, Svetlana V., Yamamoto, Masaki, Hasnain, S. Samar
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2019
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608623/
https://ncbi.nlm.nih.gov/pubmed/31316819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252519008285
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